Restoring cellular energy deficits at the root of heart disease

At Imbria, we are using our deep understanding of energy metabolism to develop novel therapies designed to substantially improve the lives of patients with life-altering cardiometabolic disorders. Our clinical stage pipeline is focused on restoring or improving the cell’s ability to produce energy in cardiovascular diseases where energetic impairment is a fundamental contributor.

Our lead program, ninerafaxstat, has completed Phase 2 clinical trials in non-obstructive hypertrophic cardiomyopathy (nHCM), stable angina, and early-stage heart failure with preserved ejection fraction (pre-HFpEF).

Our Team

Our team is uniquely positioned to execute our mission of translating our deep understanding of cellular metabolism into medicines that improve the lives of patients with limited or inadequate treatment options.

Meet our team

Our Values

Our values provide guidance on how we act internally and with the external world to fulfill our mission of improving the lives of patients with limited or inadequate treatment options.

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